Diseases that affect multiple systems (e.g., sarcoidosis)
Signs & symptoms
Patients will remain asymptomatic for many years (compensation due to the compliant left atrium dilating and keeping pulmonary venous pressures stable)
Holmes K, Gibbison B, Vohra HA. Mitral valve and mitral valve disease. BJA Education. 2017;17(1):1-9.
Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014; 63:e57.